Management Team

Bone Marrow Transplant

Overview

Advanced, Infection-Controlled Transplant Care for Adult and Paediatric Patients

Bone Marrow Transplant (BMT), also known as stem cell transplant, is a specialised treatment used to replace diseased or damaged bone marrow with healthy stem cells. It is often a life-saving intervention for both adults and children with blood cancers, bone marrow failure syndromes, and genetic disorders.

At Sir H. N. Reliance Foundation Hospital, we offer a comprehensive Bone Marrow Transplant program for both adult and paediatric patients, designed to deliver high-precision, outcome-driven care in a highly controlled environment.

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Our BMT program addresses a wide spectrum of complex haematological conditions:

In Adults:

  • Leukemia (acute and chronic)
  • Lymphoma
  • Multiple myeloma
  • Aplastic anaemia

In Children:

  • Thalassemia
  • Sickle cell disease
  • Pediatric leukemias
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  • Autologous Transplant – using patient’s own stem cells
  • Allogeneic Transplant – using donor stem cells
  • Haploidentical Transplant – half match donor option
  • Matched Unrelated Donor Transplant
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Bone Marrow Transplant (BMT) is a potentially life-saving treatment for a wide range of cancerous and non-cancerous blood, immune, and genetic disorders. It is typically recommended when the bone marrow is unable to produce healthy blood cells or when conventional treatments are no longer effective.

Blood Cancers (Hematologic Malignancies)

BMT is commonly used in the treatment of:

  • Acute Lymphoblastic Leukaemia (ALL)
  • Acute Myeloid Leukaemia (AML)
  • Chronic Leukaemia
  • Hodgkin’s Lymphoma
  • Non-Hodgkin’s Lymphoma
  • Multiple Myeloma
  • Myelodysplastic Syndromes (MDS)
  • Plasma Cell Disorders
  • Primary Amyloidosis
  • Neuroblastoma

Non-Cancerous Blood Disorders

Patients with the following conditions may benefit from BMT:

  • Aplastic Anaemia
  • Bone Marrow Failure Syndromes
  • Thalassemia Major
  • Sickle Cell Disease
  • State-of-the-Art BMT Facility
    At Sir H. N. Reliance Foundation Hospital, our dedicated Bone Marrow Transplant unit is designed to meet global clinical and safety standards, combining advanced infrastructure with a multidisciplinary, outcome-driven approach to deliver superior results across both adult and paediatric patients.
  • Advanced Infrastructure & Infection Control

    Bone marrow transplant patients are highly immunosuppressed, making infection prevention a critical success factor. Our facility is engineered to provide a highly controlled, infection-safe environment, featuring:

    • Five independent transplant rooms with HEPA filtration and 100% fresh air systems
    • Positive-pressure gradients to maintain sterile conditions
    • Antimicrobial-coated surfaces, infection-resistant flooring, and dust-free wall systems
    • Dedicated ante-rooms for medication preparation, adding an extra layer of safety
  • Multidisciplinary Expert Care 

    Our BMT program is led by expert haemato-oncologists and supported by a highly specialised, collaborative team, ensuring comprehensive care at every stage:

    • Intensivists and critical care specialists
    • Infectious disease experts
    • Paediatric specialists for child-focused transplant care
    • Nephrology (renal) team
    • Specialised transplant nursing staff
    • Clinical dieticians and rehabilitation experts

    This ecosystem is further strengthened by:

    • Advanced blood transfusion services
    • Cutting-edge genetic and molecular diagnostics for precision treatment
  • Comprehensive Safety Protocols

    Recognising the high risk of infection during BMT, we implement stringent safety protocols across infrastructure, personnel, and processes:

    • Continuous monitoring through regular air and water cultures
    • Rigorous screening of patients and visitors for resistant organisms
    • Vaccination protocols for all staff and dedicated food safety systems
    • Restricted access to maintain a sterile treatment environment
  • International Standards & Outcomes

    Our clinical protocols are aligned with JCI and NABH standards, ensuring outcomes comparable to leading global centres. The program is designed to deliver:

    • Improved survival outcomes
    • Reduced infection-related complications
    • Faster recovery timelines
  • Patient-Centric Experience

    Beyond clinical excellence, the program is designed to support patients and families through a demanding journey:

    • Private, premium care environments
    • Paediatric-sensitive care models for children
    • Emotional and nutritional support systems
    • Family-inclusive care approach

    These measures ensure maximum patient safety during the most critical phases of treatment, supporting better clinical outcomes and recovery.

  • Evaluation & Planning: Detailed diagnostics, disease assessment, and donor matching
  • Conditioning Therapy: Chemotherapy and/or radiation to prepare the body
  • Stem Cell Infusion: A controlled infusion process similar to blood transfusion
  • Recovery & Engraftment: Close monitoring in a sterile environment until new cells function effectively

For More Information

Consult our specialists to explore treatment options, donor matching, and personalised care pathways for adult and paediatric patients.


 

FAQs

A Bone Marrow Transplant is a treatment where damaged or diseased bone marrow is replaced with healthy stem cells to restore normal blood cell production.

The program is built on a strong combination of clinical excellence, infrastructure, and patient experience:

  • Best Clinical Outcomes through evidence-based treatment protocols
  • Top Tier Transplant Specialists managing complex and high-risk cases
  • Transparent Outcomes, ensuring patients are clearly informed at every stage
  • Low Infection Rates, supported by strict infection control practices
  • Zero Infection Design infrastructure to minimise risk during recovery
  • Privacy-led 5 Exclusive Suites, offering comfort and confidentiality
  • International Patient Readiness, with seamless support for overseas patients 

  • Blood cancers (leukaemia, lymphoma, myeloma)
  • Aplastic anaemia
  • Thalassemia and sickle cell disease

  • Autologous transplant (using patient’s own stem cells)
  • Allogeneic transplant (using donor stem cells)
    • Full match sibling donor Transplant
    • Haploidentical transplant (half-matched donor, usually a family member)
    • Matched unrelated donor transplant (MUD)

Safety is driven by:

  • Zero Infection Design environments
  • Continuous monitoring by specialised transplant teams
  • Proven protocols contributing to low infection rates 

It refers to a specialised care environment designed to reduce infection risks through:

  • Controlled air filtration systems
  • Isolation protocols
  • Dedicated transplant units 

This is critical during the immune-compromised phase of recovery.

You will be cared for by top tier transplant specialists supported by a multidisciplinary team, ensuring comprehensive and coordinated care.

Patients receive:

  • Clear communication on expected outcomes
  • Honest discussions around risks and recovery timelines
  • Continuous updates during treatment 

Patients are treated in privacy-led exclusive suites, designed to provide:

  • High levels of comfort
  • Reduced infection exposure
  • Personalised care and confidentiality 

Yes. The hospital is fully equipped with international patient readiness, including:

  • Pre-arrival coordination
  • Travel and visa assistance
  • Dedicated support teams
  • Post-treatment follow-up 

  • Pre-transplant evaluation
  • Conditioning therapy (chemotherapy ± radiation)
  • Stem cell infusion (IV-based)
  • Engraftment and recovery 

  • Hospital stay: typically, 3–4 weeks
  • Full recovery: 3–6 months or longer

  • Infection (minimised through advanced protocols)
  • Graft-versus-host disease (in donor transplants)
  • Temporary side effects from treatment 

All risks are proactively managed by the care team.

Yes. Most patients gradually resume normal routines after recovery, with regular follow-ups.

  • Nutritional and lifestyle guidance
  • Psychological counselling
  • Infection prevention education
  • Long-term follow-up care 

It is designed around three core pillars:

  • Clinical Excellence (best clinical outcomes, top specialists)
  • Infrastructure Excellence (Zero Infection Design, low infection rates)
  • Experience Excellence (privacy-led suites, international readiness)